abstract：BACKGROUND:Although in the developed world the intracranial pressure (ICP) monitor is considered the standard of care for patients with severe traumatic brain injury (TBI), its usefulness to direct treatment decisions has never been tested rigorously. OBJECTIVE:The primary focus was to conduct a high-quality, randomiz...

journal_title：Neurosurgery

authors： Chesnut RM,Temkin N,Carney N,Dikmen S,Pridgeon J,Barber J,Celix JM,Chaddock K,Cherner M,Hendrix T,Lujan S,Machamer J,Petroni G,Rondina C,Videtta W

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The standard treatment of resected brain metastasis is whole-brain radiotherapy (WBRT). To avoid the potential toxicity of WBRT and to improve local control, we have used radiosurgery alone to the surgical cavity. OBJECTIVE:To demonstrate the rates of local control, new intracranial metastasis, and overall ...

journal_title：Neurosurgery

authors： Robbins JR,Ryu S,Kalkanis S,Cogan C,Rock J,Movsas B,Kim JH,Rosenblum M

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Dramatic growth of meningiomas is occasionally encountered during pregnancy. While cell proliferation is often assumed, hemodynamic changes have also been touted as a cause. OBJECTIVE:We identified 17 meningiomas resected during pregnancy or within 3 weeks post-partum and characterized them to determine the...

journal_title：Neurosurgery

authors： Lusis EA,Scheithauer BW,Yachnis AT,Fischer BR,Chicoine MR,Paulus W,Perry A

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Improved understanding of rod fracture (RF) in adult spinal deformity could be valuable for implant design, surgical planning, and patient counseling. OBJECTIVE:To evaluate symptomatic RF after posterior instrumented fusion for adult spinal deformity. METHODS:A multicenter, retrospective review of RF in ad...

journal_title：Neurosurgery

authors： Smith JS,Shaffrey CI,Ames CP,Demakakos J,Fu KM,Keshavarzi S,Li CM,Deviren V,Schwab FJ,Lafage V,Bess S,International Spine Study Group.

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Lumbar discectomy is the most commonly performed spine procedure. Academic spine centers with potentially differing caseloads and experience may have different outcomes. OBJECTIVE:To determine whether the choice of center in which surgery is performed affects lumbar discectomy outcomes. METHODS:Spine Patie...

journal_title：Neurosurgery

authors： Desai A,Bekelis K,Ball PA,Lurie J,Mirza SK,Tosteson TD,Zhao W,Weinstein JN

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Although previous evidence suggests that the cognitive effects of concussions are cumulative, the effect of time interval between repeat concussions is largely unknown. OBJECTIVE:To determine the effect of time interval between repeat concussions on the cognitive function of mice. METHODS:We used a weight-...

journal_title：Neurosurgery

authors： Meehan WP 3rd,Zhang J,Mannix R,Whalen MJ

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Cerebrovascular pressure reactivity is the principal mechanism of cerebral autoregulation. Assessment of cerebral autoregulation can be performed by using the mean flow index (Mx) based on transcranial Doppler ultrasonography. Cerebrovascular pressure reactivity can be monitored by using the pressure reactiv...

journal_title：Neurosurgery

authors： Budohoski KP,Czosnyka M,de Riva N,Smielewski P,Pickard JD,Menon DK,Kirkpatrick PJ,Lavinio A

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Spinal cord cavernous malformations (CMs) are associated with 2 types of angiographically occult "cryptic venous anomalies," which differ in location with respect to the spinal cord. The anatomic distinction between superficial and intramedullary is important in that the latter heighten the risks of CM resec...

journal_title：Neurosurgery

authors： Pearl MS,Chen JX,Gregg L,San Millàn D,Belzberg A,Jallo G,Gailloud P

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:Although the use of proximal artery occlusion, or hunterian ligation, for the treatment of intracranial aneurysms has decreased greatly over the past decades, this approach still finds use for certain giant and complex aneurysms. The main risks of artery sacrifice are ischemic complications bu...

journal_title：Neurosurgery

authors： Arnaout OM,Rahme RJ,Aoun SG,Daou MR,Batjer HH,Bendok BR

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:Because of their rarity, the pathogenesis and clinical features of isolated spinal artery aneurysms are still unclear, and their diagnoses and treatments are challenging. We report a case of an isolated posterior spinal artery aneurysm and review previous reports thoroughly to identify the gen...

journal_title：Neurosurgery

authors： Kim HJ,Choi IS

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Obtaining a watertight reconstruction with a fat graft with wide sellar exposures can be challenging, including the risk of reinstating mass effect with the fat graft. The alternative, a vascularized pedicle nasoseptal flap, may require several days to heal and still has a > 5% cerebrospinal fluid (CSF) leak...

journal_title：Neurosurgery

authors： Bergsneider M,Xue K,Suh JD,Wang MB

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Data on radiotherapy for trigeminal schwannomas (TSs) and comparison of stereotactic radiosurgery (SRS) with fractionated stereotactic radiotherapy (FSRT) are limited. OBJECTIVE:We present a large retrospective review of our institutional experience treating TSs with SRS and FSRT. We also describe a flare p...

journal_title：Neurosurgery

authors： Champ CE,Mishra MV,Shi W,Siglin J,Werner-Wasik M,Andrews DW,Evans JJ

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Silent corticotroph adenomas (SCAs) are clinically nonfunctioning pituitary adenomas (NFPAs) with positive staining for corticotropin (ACTH) by immunohistochemistry. Whether SCAs behave more aggressively than NFPAs without ACTH immunoreactivity (ACTH negative) remains controversial. OBJECTIVE:To compare cha...

journal_title：Neurosurgery

authors： Ioachimescu AG,Eiland L,Chhabra VS,Mastrogianakis GM,Schniederjan MJ,Brat D,Pileggi AV,Oyesiku NM

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:En bloc resection of primary sacral tumors has a demonstrated survival benefit. Total and high sacral amputations are traditionally performed by using a staged anterior and subsequent posterior approach. However, we have found that en bloc resection and biomechanical reconstruction of the spinal column is po...

journal_title：Neurosurgery

authors： Clarke MJ,Dasenbrock H,Bydon A,Sciubba DM,McGirt MJ,Hsieh PC,Yassari R,Gokaslan ZL,Wolinsky JP

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Posttraumatic syringomyelia affects approximately 28% of spinal cord injury patients, and current treatments are often ineffective. The pathogenesis of this condition remains poorly understood. Previous reports have focused on pathways and mechanisms of fluid inflow; however, disturbances of fluid outflow me...

journal_title：Neurosurgery

authors： Wong J,Hemley S,Jones N,Cheng S,Bilston L,Stoodley M

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:In Asian populations, moyamoya disease has a well-defined phenotype including a bimodal age of presentation with children typically presenting with ischemic phenomena and adults presenting with hemorrhage. Studies have provided evidence that moyamoya disease in the United States may exhibit a different pheno...

journal_title：Neurosurgery

authors： Starke RM,Crowley RW,Maltenfort M,Jabbour PM,Gonzalez LF,Tjoumakaris SI,Randazzo CG,Rosenwasser RH,Dumont AS

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Subdural hematoma (SDH) in patients with cancer is poorly described, and its frequency and causes may have changed with recent oncologic advances. OBJECTIVE:We conducted an analysis of the clinical and radiographic features, etiologies, treatments, and outcomes of patients with SDHs and cancer. METHODS:We ...

journal_title：Neurosurgery

authors： Reichman J,Singer S,Navi B,Reiner A,Panageas K,Gutin PH,Deangelis LM

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Placement of spinal cord stimulating paddle leads has traditionally been performed under local anesthesia with intravenous sedation to allow intraoperative confirmation of appropriate placement. It may be difficult to maintain appropriate sedation in certain patients because of medical comorbidities. Further...

journal_title：Neurosurgery

authors： Mammis A,Mogilner AY

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Although the combined petrosal approach has significant advantages for medium to large petroclival lesions, it carries the risk of a few major complications. The cerebrospinal fluid leak rate with this approach has been reported to be as high as 15%. OBJECTIVE:To describe an innovative technique of watertig...

journal_title：Neurosurgery

authors： Kusumi M,Fukushima T,Aliabadi H,Mehta AI,Noro S,Rosen CL,Fujii K

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The lower thoracic spine is a complicated area within the vertebral column because of its anatomic complexity and inaccessibility. A variety of surgical procedures have been applied to access lower thoracic spinal lesions. When hard compressive pathologies are located on the ventral side of the dura, existin...

journal_title：Neurosurgery

authors： Lee SE,Jahng TA,Chung CK,Kim HJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Stent-assisted coiling in the setting of subarachnoid hemorrhage remains controversial. Currently, there is a paucity of data regarding the utility of this procedure and the risks of hemorrhagic and ischemic complications. OBJECTIVE:To assess the utility of stent-assisted coil embolization and pretreatment ...

journal_title：Neurosurgery

authors： Amenta PS,Dalyai RT,Kung D,Toporowski A,Chandela S,Hasan D,Gonzalez LF,Dumont AS,Tjoumakaris SI,Rosenwasser RH,Maltenfort MG,Jabbour PM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Distal middle cerebral artery (MCA) aneurysms frequently have nonsaccular morphology that necessitates trapping and bypass. Bypasses can be difficult because efferent arteries lie deep in the opercular cleft and may not be easily identifiable. OBJECTIVE:We introduce the "flash fluorescence" technique, which...

journal_title：Neurosurgery

authors： Rodríguez-Hernández A,Lawton MT

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Somatosensory evoked potential (SSEP) monitoring is used during intracranial aneurysm surgery to track the effects of anesthesia, surgical manipulation, and temporary clipping. OBJECTIVE:To present the outcomes of 663 consecutive patients (691 cases) treated surgically for intracranial aneurysms who underwe...

journal_title：Neurosurgery

authors： Wicks RT,Pradilla G,Raza SM,Hadelsberg U,Coon AL,Huang J,Tamargo RJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Traumatic brain injuries remain a treatment enigma with devastating late results. As terminally differentiated tissue, the brain retains little capacity to regenerate, making early attempts to preserve brain cells after brain injury essential. OBJECTIVE:To resuscitate damaged tissue by modulating edema, sol...

journal_title：Neurosurgery

authors： Argenta LC,Zheng Z,Bryant A,Tatter SB,Morykwas MJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Carotid plaque characteristics influence future risk of stroke considerably. However, the severity of stenosis does not accurately reflect plaque burden in patients with expansive arterial remodeling. OBJECTIVE:To determine the therapeutic outcome of symptomatic carotid low-grade stenosis with vulnerable pl...

journal_title：Neurosurgery

authors： Yoshida K,Sadamasa N,Narumi O,Chin M,Yamagata S,Miyamoto S

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Lesions in the insula and basal ganglia can be risky to resect because of their depth and proximity to critical structures, particularly in the dominant hemisphere. Transsylvian approaches shorten the surgical distance to these lesions, preserve perisylvian temporal and frontal cortex, and minimize brain tra...

journal_title：Neurosurgery

authors： Potts MB,Chang EF,Young WL,Lawton MT,UCSF Brain AVM Study Project.

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Epilepsy surgery involving the cingulate gyrus has been mostly presented as case reports, and larger series with long-term follow-up are not published yet. OBJECTIVE:To report our experience with focal epilepsy arising from the cingulate gyrus and surrounding structures and its surgical treatment. METHODS:...

journal_title：Neurosurgery

authors： von Lehe M,Wagner J,Wellmer J,Clusmann H,Kral T

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Achieving seizure control in patients with low-grade temporal lobe gliomas or glioneuronal tumors remains highly underappreciated, because seizures are the most frequent presenting symptom and significantly impact patient quality-of-life. OBJECTIVE:To assess how the extent of temporal lobe resection influen...

journal_title：Neurosurgery

authors： Englot DJ,Han SJ,Berger MS,Barbaro NM,Chang EF

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Iliac screw fixation is a powerful tool used by spine surgeons to achieve fusion across the lumbosacral junction for a number of indications, including deformity, tumor, and pseudarthrosis. Complications associated with screw placement are related to blind trajectory selection and excessive soft tissue disse...

journal_title：Neurosurgery

authors： Shin JH,Hoh DJ,Kalfas IH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Deep brain stimulation electrode placement with interventional magnetic resonance imaging (MRI) has previously been reported using a commercially available skull-mounted aiming device (Medtronic Nexframe MR) and native MRI scanner software. This first-generation method has technical limitations that are inhe...

journal_title：Neurosurgery

authors： Larson PS,Starr PA,Bates G,Tansey L,Richardson RM,Martin AJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Accurate placement of a probe to the deep regions of the brain is an important part of neurosurgery. In the modern era, magnetic resonance image (MRI)-based target planning with frame-based stereotaxis is the most common technique. OBJECTIVE:To quantify the inaccuracy in MRI-guided frame-based stereotaxis a...

journal_title：Neurosurgery

authors： Thani NB,Bala A,Lind CR

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Free radicals and lipid peroxidation are thought to be related to the vasospasm generation after subarachnoid hemorrhage (SAH). Plasma platelet-activating factor-acetyl hydrolase (PAF-AH) degrades phospholipids with an oxidatively modified fatty acyl chain. OBJECTIVE:To compare plasma PAF-AH activity and fr...

journal_title：Neurosurgery

authors： Hirashima Y,Doshi M,Hayashi N,Endo S,Akazawa Y,Shichiri M,Yoshida Y

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The incidence of symptomatic adjacent segment disease (ASD) after anterior cervical diskectomy and fusion (ACDF) was reported as 2.9%/y in a previous cohort of 374 patients. Few other data corroborate the incidence and natural history of ASD. OBJECTIVE:To calculate the incidence of ASD after ACDF that requi...

journal_title：Neurosurgery

authors： Wu JC,Liu L,Wen-Cheng H,Chen YC,Ko CC,Wu CL,Chen TJ,Cheng H,Su TP

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Intraoperative measurements of cerebral blood flow are of interest during vascular neurosurgery. Near-infrared indocyanine green (ICG) fluorescence angiography was introduced for visualizing vessel patency intraoperatively. However, quantitative information has not been available. OBJECTIVE:To report our ex...

journal_title：Neurosurgery

authors： Kamp MA,Slotty P,Turowski B,Etminan N,Steiger HJ,Hänggi D,Stummer W

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Knowledge of the individual course of the optic radiations (ORs) is important to avoid postoperative visual deficits. Cadaveric studies of the visual pathways are limited because it has not been possible to separate the OR from neighboring tracts accurately and results may not apply to individual patients. D...

journal_title：Neurosurgery

authors： Wu W,Rigolo L,O'Donnell LJ,Norton I,Shriver S,Golby AJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Recent studies have focused on antiplatelet (AP) use in intracerebral hemorrhage (ICH) patients. Several outcome predictors have been debated, but influences on mortality and outcome still remain controversial, especially for different ICH locations. OBJECTIVE:To investigate the characteristics and function...

journal_title：Neurosurgery

authors： Kuramatsu JB,Mauer C,Kiphuth IC,Lücking H,Kloska SP,Köhrmann M,Huttner HB

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Cerebral vasospasm is an independent predictor of poor outcome after subarachnoid hemorrhage (SAH). The nitric oxide-cyclic guanosine monophosphate (NO-cGMP) vasodilatory pathway is strongly implicated in its pathophysiology. Preliminary studies suggest that phosphodiesterase 5 (PDE5), an enzyme that degrade...

journal_title：Neurosurgery

authors： Han BH,Vellimana AK,Zhou ML,Milner E,Zipfel GJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Surgical treatment of C2 tumors remains challenging. Because of the deep location and unique anatomical complexity, anterior exposure in this region is considered difficult and dangerous, and few reports concerning anterior tumor resection and reconstruction exist. OBJECTIVE:To describe a technique of seque...

journal_title：Neurosurgery

authors： Yang X,Wu Z,Xiao J,Teng H,Feng D,Huang W,Chen H,Wang X,Yuan W,Jia L

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:Deep brain stimulation (DBS) of the bilateral globus pallidus internus (GPi) has been used effectively to treat dystonia. We report a patient with severe Meige syndrome who received bilateral GPi DBS with good improvement in symptoms during the first 24-month stimulation therapy. To decrease e...

journal_title：Neurosurgery

authors： Tai CH,Wu RM,Liu HM,Tsai CW,Tseng SH

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND IMPORTANCE:We report an extremely rare case with mirror-site spinal dural arteriovenous fistulas (DAVFs) at the craniocervical junction. Although multiple spinal DAVFs have been reported in the literature, complete mirror-site lesions with fistulas and feeding arteries in the symmetric position have not ...

journal_title：Neurosurgery

authors： Oshita J,Yamaguchi S,Ohba S,Kurisu K

更新日期：2011-11-01 00:00:00